Metacarpal bone destruction predicts erosions in rheumatoid arthritis. Researcher state that 3 months bone loss play a substantial role in the development of erosions [1], another study reveals that ‘bone loss positive’ patients after one year face a greater risk of erosions at three, five and 10 years [2, 3, 7, 8] than patients with stable DXR-BMD.
Hand bone loss after 1-year follow-up predicts radiographic progression after 5 and 10 years.
Hoff, van der Heijde, Landewe, Haugeberg, Kvien
Hand bone loss in the first three months and baseline MRI bone marrov edema predicts one-year change in MRI erosions.
Bøyesen, Haavardsholm, Østergaard, Haugeberg, Schilvold, Kvien
DXR is a FDA-approved, CE-marked and patented way to quantify forearm bone mineral density on digital hand radiographs. DXR is available as a service online through our Internet laboratory, dxr-online. Contact us to get access to our services. Send hand radiographs to the laboratory and get results in return. The worldwide research and first clinical laboratory is now operational.
DXR-online has processed several randomized treatment strategy studies with consistent results. The more aggressive RA treatment the less bone is lost.
The three middle metacarpals in a standard digital radiograph of the hand are automatically identified and segmented using Digital X-ray Radiogrammetry (DXR). More than 1500 geometrical dimension measurements are used to derive Bone Mineral Density with unsurpassed precision.
